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		This flexible and easy to use computer program allows the user to investigate the effects of the various operating parameters in CE. The program can be used to display the simulated peaks of analytes chosen from a database of over 100 compounds. The program simulates the effect of varying any of the numerous parameters that can be varied in the real life situation. The database entry for each solute include the pKa value and the electrophoretic mobility. The database can easily be updated to include user specific compounds.
Whenever the user makes a change to any of the operating parameters, the package immediately recalculates and displays the new simulated electropherogram. The values of each variable can easily be changed using the comprehensive mouse controlled pull down menus. In addition to the simulated peaks the simulation reports migration time, resolution, electrical current, peak area and electrophoretic mobility. The package also includes a number of exercises that can be used in the following fashion with predetermined test mixtures. The test mixtures used in the exercises include mixtures of acidic, basic and neutral compounds. A test mixture consisting of a compound together with trace level related impurities is also included. The user can enter details of their own compounds of interest in order to carry out user specific optimisations. Understanding the principles of CE and the effects of various operating parameters. Method development aid for both free solution electrophoresis, MECC and supports even Chiral Separations. Optimisation of method in terms of achieving the required resolution, sensitivity , current level and analysis time. Examine the robustness of a method by simultaneous adjustment of operating parameters.

Variable Parameters include:

Electrolyte Ionic strength pH, additives micellar additives chiral additives

Capillary Total length length to detector inner and outer diameter zeta potential capillary material type

Equipment Detector type applied voltage polarity injection volume (pressure and time) operating temperature cooling mechanism.

Ordering Information
To order CE and MECC Computer Simulator Package, please contact us
Tel: +44 (0)1506 858505 or Fax: +44 (0)1506 858506
sales@capitalhplc.com

Questions or enquires regarding the contents of these pages
or any capital HPLC product email: info@capitalhplc.com.