High Purity Silica Column

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All the advantages and advances of HPLC Columns that have been favored for over 30 years... plus!   EVOLUTIONARY SUPPORTS FOR HPLC • Performance Improvements • Unique Selectivity • Silicon-Carbon Attachments of Bonded Phase The Cogent TYPE-C SilicaTM is the next step in the evolution of State of the Art HPLC silica supports. Our proprietary and patented process of making high purity, spherical silica produces a very unique silica surface that is not a hybrid but is populated with silicon-hybride groups (Si-H) instead of the traditional silanol (Si-OH). Combining the advantages of familiar, high purity type-B silica with our new surface gives the modern chromatographer many new options for normal phase and reverse phase separations. Highly efficient and reproducible, these columns will perform beyond your imagination. Un-bonded silica columns that produce reverse phase separations, Cholesterol bonded columns that perform normal phase and reverse phase separations at the same time and Bidentate C18TM columns with 2 points of attachment for stability, are available without the siloxane bond that is susceptible to hydrolysis. These columns give you incredible stability even in 100% aqueous conditions without loss of resolution. LCMS and preparative chomatographers love these phases because there is no organic moiety to ‘bleed’. Method Development chemists love them because they often eliminate the need to choose a gradient method and give separation of highly polar compounds that normally will not retain on any HPLC column in reverse phase solvents. Cogent TYPE-CTM Products are supplied with the MicroSolv Super-Link SystemTM (SLS) hardware.   Cogent 5µm Spherical Silica   The development of spherical shaped silica particles of 10µm and later 5µm particle size proved to be a great advancement in HPLC supports. The uniformity of shape and size allowed for better packed columns which resulted in an increase in precision and ruggedness. These tightly controlled particles did not create “fines” as irregular shaped particles do resulting in columns that lasted longer and were more stable. Even with this improvement, HPLC columns still suffered from frequent tailing problems when basic compounds were separated at desired pH. Today, Reverse Phase Separations are predominantly being performed on silica bonded with hydrocarbons mostly C8 and C18. TYPE-C Silica

Specifications
Mean Particle Diameter	4.2um
Pore Diameters	100‰
Surface Area	350m2/g
Pore volume	0.92ml/gm

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